CD46 as a Measles Receptor: Form Follows Function
نویسندگان
چکیده
منابع مشابه
Emotions: form follows function.
Emotion research has been divided by debate as to whether emotions are universal in form or cognitively constructed. We review an emerging approach that focuses on function rather than form. Functional affective science suggests that the particular origin of an emotion is relatively unimportant; instead, emotions can be understood in terms of a rapidly deployed set of mechanisms that structure ...
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Editor’s note: This Commentary is a companion to Refractory Depression, Fatigue, Irritable Bowel Syndrome, and Chronic Pain: A Functional Medicine Case Report on page 104 (available at: www.thepermanentejournal.org/ issues/2016/fall/6239-ibs.html). Also note that material describing the foundation and practice of Functional Medicine has been excerpted, with permission, from Introduction to Func...
متن کاملHuman membrane cofactor protein (CD46) acts as a cellular receptor for measles virus.
A monoclonal antibody (MCI20.6) which inhibited measles virus (MV) binding to host cells was previously used to characterize a 57- to 67-kDa cell surface glycoprotein as a potential MV receptor. In the present work, this glycoprotein (gp57/67) was immunopurified, and N-terminal amino acid sequencing identified it as human membrane cofactor protein (CD46), a member of the regulators of complemen...
متن کاملAnalysis of receptor (CD46, CD150) usage by measles virus.
In order to investigate which measles virus (MV)-strains use CD46 and/or CD150 (signalling lymphocytic activation molecule, SLAM) as receptors, CHO cells expressing either recombinant CD46 or SLAM were infected with a panel of 28 MV-strains including vaccine strains, wild-type strains with various passage histories and recombinant viruses. We found that SLAM served as a common receptor conferri...
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ژورنال
عنوان ژورنال: Virology
سال: 2000
ISSN: 0042-6822
DOI: 10.1006/viro.2000.0613